Prof. Dr. Sebastian Dendorfer
OTH Regensburg (Germany)

Towards a deeper understanding of Pelvic Floor Disorders via Biomechanical Models

Abstract
Millions of people worldwide are affected by pelvic floor disorders, which significantly impair their quality of life. Despite their prevalence, understanding the underlying biomechanical mechanisms remains a challenge. This presentation will explore the role of advanced biomechanical modelling in uncovering the complexity of PFDs. By integrating patient-specific data and forward and backward musculoskeletal simulations, we can analyse pelvic floor function and dysfunction with unprecedented precision. The presentation will highlight recent advances in modelling techniques, their potential clinical applications and the potential to improve the diagnosis and prevention of PFD.

Bio
Prof. Dr.-Ing. Sebastian Dendorfer is a professor of Biomechanics at OTH Regensburg, German. His research focuses on virtual human models for prevention and rehabilitation in orthopedic biomechanics. A graduate in Civil Engineering and Computational Mechanics, he earned his Ph.D. on bone fatigue behavior and previously worked with AnyBody Technology A/S. Since 2011, he has been leading the Biomechanics Lab at OTH Regensburg. He is also director of the Regensburg Center for Health Science and Technology.


Assoc. Prof. Priv.-Doz. Dr. Hans Kainz
University of Vienna (Austria)

Exploring the interplay between anatomy, motion and loads: Insights from in silico simulations for clinical advances

Abstract
In-silico simulations are revolutionizing clinical biomechanics and, more recently, mechanobiology by providing deeper insights into musculoskeletal function. This keynote will explore how advanced computational techniques – integrating 3D motion analysis, medical imaging, and biomechanical modeling – enhance our understanding of in-vivo loads in both healthy individuals and clinical populations.
The talk will examine how movement strategies, anatomical variations, and orthopedic interventions influence musculoskeletal conditions, with a focus on adolescents with patellofemoral instability, children with cerebral palsy, and those with idiopathic torsional deformities. By bridging simulation technologies with clinical practice, we can drive innovation in musculoskeletal research and improve therapeutic strategies, ultimately enhancing patient outcomes.

Bio
Hans Kainz is an Associate Professor and Head of the Neuromechanics Group at the University of Vienna. He holds a PhD in Biomechanics from Griffith University and has gained extensive international experience as a Rehabilitation Engineer at Queensland Children’s Hospital in Australia and as a Postdoctoral Research Fellow at KU Leuven in Belgium. His research explores the complex interplay between anatomy, movement, in-vivo loads, and bone growth, with a strong focus on improving clinical decision-making and advancing rehabilitation strategies for individuals with musculoskeletal disorders. Recognized for his contributions to the field, he has received multiple prestigious awards, including a recent ERC Consolidator Grant.